Weaned piglets affected by enterotoxigenic Escherichia coli (ETEC) may experience post-weaning diarrhea, resulting in growth retardation and harm to the piglets’ innate and adaptive immune systems.
These risk factors increase piglet illness and death, resulting in significant economic losses in the global swine industry.
Antibiotics as growth promoters have been used sparingly due to concerns regarding resistant pathogens, residue buildup in animal products, and environmental damage.
For these reasons, the quest for alternatives to antibiotic growth promoters, like pro-and prebiotics, organic acids, enzymes, and plant extracts, has gained traction. Plant extract seems to be one of the most frequently acknowledged prospective antibiotic alternatives.
Guava is a tropical fruit and medicinal plant that is primarily found in tropical and subtropical regions. Guava leaf extract, used as herbal medicine to treat respiratory and gastrointestinal illnesses, is said to include phenolics, triterpenoids, and other chemicals with antibacterial, antioxidant, and anti-inflammatory properties.
Pruning is commonly employed to boost growth and impact fruiting in guava. Hence, residual guava leaves from pruned procedures are prospective sources of natural feed additives that could be used as an alternative to in-feed antibiotics.
Recent research has shown that fresh guava leaves have antidiarrheal action in piglets with diverse diarrheas. Many studies have shown that fresh guava leaves can reduce diarrhea and increase intestinal anti-inflammatory capabilities in piglets infected with ETEC.
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